Scientific Findings | Faxitron Bioptics LLC

Ultrastructural Analysis of Vascular Calcifications in Uremia

High-resolution radiographic images of four artery segments were taken under identical conditions by means of a Faxitron Model MX-20 (Faxitron x-ray Corp., Wheeling, IL).

Morphological changes and quality of papaya seeds as correlated to their location within the fruit and ripening stages

The objective of this study was to evaluate the morphological and physiological quality of papaya seeds extracted at different ripeness stages of the fruit and the position inside of the fruit

Identification of the haematopoietic stem cell niche and control of the niche size

High-resolution X-rays (Faxitron MX-20) of bone and bone histomorphometry (OsteoMetrics, Inc.) were performed at the University of Missouri–Kansas City School of Dentistry

TAK1–TAB2 Signaling Contributes to Bone Destruction by Breast Carcinoma Cells

Formation of bone lesions was monitored biweekly using full-body X-ray imaging with a Faxitron MX-20 X-ray machine.

Radiographic analysis of zebrafish skeletal defects

Radiography was performed in a Faxitron MX-20 cabinet X-ray machine, for 3–4 s at 17–20 kVolts

Otitis media in the Tgif knockout mouse implicates TGFb signalling in chronic middle ear inflammatory Disease

Radiography was performed using a Faxitron Mx-20 DC-4 specimen X-ray System

Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease

Radiographs were generated using a Faxitron Radiography System


1 month old C/EBPβ heterozygous transgenic and wild type littermate controls from both sexes were sacrificed by CO2 asphyxiation, the femurs were aseptically removed, and used to recover bone marrow stromal cells

Integrin αvβ3 expression confers on tumor cells a greater propensity to metastasize to bone

At the end of the experiments, animals were examined by radiography: animals were laid on their backs against MIN R 2000 films and exposed to 18 kV for 30 s using a cabinet X-ray system

Extracellular Engagement of α6 Integrin Inhibited Urokinase-Type Plasminogen Activator–Mediated Cleavage and Delayed Human Prostate Bone Metastasis

Digital radiographs were collected on live animals 4, 5, and 6 weeks after tumor cell injection using a Faxitron MX-20 machine

Dual function of ERRαin breast cancer and bone metastasis formation:implication of VEGF and osteoprotegerin

Radiographs of animals were taken at 35 days after inoculation using X-ray

Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone

The present study demonstrates that tissues are extraordinarily sensitive to modest changes in the type of PKA signaling

A Self-inactivating γ-Retroviral Vector Reduces Manifestations of Mucopolysaccharidosis I in Mice

Bone radiographs were taken using an MX-20 Specimen Radiography System (Faxitron, Lincolnshire, IL) at 20 kV for 15 seconds. Bone mineral density scans were performed using a PixiMus dual energy X-ray absorption machine

Growing out of a caste – reproduction and the making of the queen mole-rat

These paired females were closely observed during the study and underwent weekly radiograph

High-throughput behavioral screening method for detecting auditory response defects in zebrafish

Dishes containing zebrafish oriented for lateral or ventral views were placed on Kodak SO-253 High-Speed Holographic Film in a Faxitron cabinet radiography system

The Osterix Transcription Factor Down-Regulates Interleukin-1 α Expression in Mouse Osteosarcoma Cells

Magnified flat radiographs were taken with a MX-20 Specimen Radiograph System

Photoacoustic tomography of joints aided by an Etanercept-conjugated gold nanoparticle contrast agent—an ex vivo preliminary rat study

To obtain histological photographs, rat tails were saved in 10% buffered formalin for 3 d. Tails were then decalcified with formic acid for 4–7 d and monitored with a Faxitron MX-20 x-ray system

Suppression of the inflammatory response in experimental arthritis is mediated via estrogen receptor α but not estrogen receptor β

X-ray photographs were examined with a Faxitron X-ray MX-20 and bone destruction was scored on a scale from 0 to 5 ranging from no damage to complete destruction

The Transforming Growth Factor-β Receptor I Kinase Inhibitor SD-208 Reduces the Development and Progression of Melanoma Bone Metastases.

Mice were x-rayed in a prone and lateral position using a Digital Faxitron MX-20 with digital camera (Faxitron x-ray, Wheeling, IL), as described previously (32)

Trichomycterus igobi, a new catfish species from the rio Iguaçu drainage: the largest head in Trichomycteridae (Siluriformes: Trichomycteridae)

Radiographs of specimens were done with a Faxitron digital x-ray system, model MX-20. Vertebral counts did not include those in the Weberian complex and compound caudal centrum


In this study, the infestation level of insects in acorns of Quercus candicans Née was determined along with its effect on germination

Sustained blockade of neurotrophin receptors TrkA, TrkB and TrkC reduces non-malignant skeletal pain but not the maintenance of sensory and sympathetic nerve fibers

Digital radiographs of the fractured femur were acquired immediately after fracture and at days 7, 10, 14, 17, 21, 28, 35, 42, 49 post-fracture

A Genetic Screen for Modifiers of the Delta1-Dependent Notch Signaling Function in the Mouse

Selected animals were analyzed with the Faxitron Specimen Radiography system model MX-20 for skeletal malformations

The Relevance of CD44 and hyaluronan interaction in osteosarcoma progression and metastasis

The development of primary tumors was visualized bi-weekly during the first 1 to 9 weeks of the experiment and then weekly until the end of the experiment by X-ray with a MX-20 DC Digital Radiography System

Increased Dickkopf-1 expression in breast cancer bone metastases

Whole body radiographs of anaesthesised animals were taken 30 days after tumour cell inoculation using an MX-20 cabinet X-ray system

X-Ray analysis to assess mechanical damage in sweet corn seeds

Seeds were submitted to mechanical damage using a BC Impact Simulator in which 965 kPa compressed air launched seeds against a steel plate at a distance of 10 cm

A Comprehensive Analysis of the Dual Roles of BMPs in Regulating Adipogenic and Osteogenic Differentiation of Mesenchymal Progenitor Cells

Most BMPs exhibited distinct abilities to regulate expression of the master regulators of four common lineages derived from MSCs

Targeted disruption of the osteoblast/osteocyte factor 45 gene (OF45) results in increased bone formation and bone mass

Femurs were examined at 2X and 3X magnification on a Faxitron model MX-20 Specimen Radiography System with Kodak Min-R 2000 Mammography film in Min-R 2000 cassettes with an intensifying screen

JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia

Rats were sacrificed on day 17. Right hind limbs were excised with surrounding tumor tissue, and microradiographs were prepared using an MX-20 X-ray system

Mechanism of shortened bones in mucopolysaccharidosis VII

Mice were sacrificed via CO2 inhalation, and legs, arms, and vertebral columns were excised and excess skin and tissue were removed. Radiographs were taken using a MX-20 Specimen Radiography System

Contest behaviour of maize weevil larvae when competing within seeds

All of the maize seeds containing eggs were observed every other day (and daily upon imminence of larval interaction) using an MX-20 specimen radiography system

Viability of recently harvested and stored Xylopia aromatica (Lam.) Mart. (Annonaceae) seeds

The seeds were distributed among cells in an acrylic plate and X-rayed with a Faxitron X Ray MX – 20 machine using X-ray film

Use of X-ray to evaluate damage caused by weevils in cowpea seeds

The X-ray was obtained by placing the acrylic plate with the seeds directly on an X-ray film measuring 18 x 24 cm, at a distance of 57 cm from the X-ray emission source

Effect of zoledronic acid on the doxycycline-induced decrease in tumour burden in a bone metastasis model of human breast cancer

Twenty-eight days after injection of the cells, high-resolution radiographic scans of all mice in the prone and lateral position were taken under inhaled isoflurane anaesthesia with a Faxitron X-ray system MX-20

A Mouse with an N-Ethyl-N-Nitrosourea (ENU) Induced Trp589Arg Galnt3 Mutation Represents a Model for Hyperphosphataemic Familial Tumoural Calcinosis

Anaesthetised mice were subjected to digital radiography at 26 kV for 3 seconds using a Faxitron MX-20 digital X-ray system

Angiostatin inhibits bone metastasis formation in nude mice through a direct anti-osteoclastic activity

Tumor cells were inoculated into the tail vein of anesthetized nude mice. Animals then received or did not receive doxycycline in the supply water for the duration of the experiments

A Mouse Model for Osseous Heteroplasia

The skin was dissected from underlying subcutaneous fat and muscle in one piece to include any gross skin lesions of the paws and tail. The skin was thoroughly washed in tap water to remove any adherent material

Enhancing Quality of Life for Breast Cancer Patients with Bone Metastases

The right femur of 20 female nude mice was injected with human breast cancer cells. The development of osteolytic lesions was monitored by weekly X-rays.

Critical Role of Calbindin-D28k in Calcium Homeostasis Revealed by Mice Lacking Both Vitamin D Receptor and Calbindin-D28k

The bones (from three to five mice in each genotype) were analyzed by peripheral quantitative computed tomography (pQCT) as well as by histological sectioning described below

A rat model of early stage osteonecrosis induced by glucocorticoids

Based on the histological results, Faxitron x-ray analysis was performed initially on a group of Wistar Kyoto rats.

Novel and Selective Small Molecule Stimulators of Osteoprotegerin Expression Inhibit Bone Resorption

After 3 and 4 weeks of treatment (4 and 5 weeks post inoculation), tumor progression was evaluated using a high resolution Faxitron X-ray system

The interplay of osteogenesis and hematopoiesis: expression of a constitutively active PTH/PTHrP receptor in osteogenic cells perturbs the establishment of hematopoiesis in bone and of skeletal stem cells in the bone marrow

Radiographic images of long bones were obtained at an energy of 30 kV for 90 s with X-OMAT TL film and processed by an automated X-ray film developer

Growth Factor Inhibits Ewing's Sarcoma Growth in a Xenograft Mouse Model

To assess bone tumor formation cells were injected into the right tibia under anesthesia. Three weeks later, digitized radiographic images were taken using a MX-20 Specimen Radiograph System

A New Species of the Neotropical Catfish Genus Trichomycterus (Siluriformes: Trichomycteridae) Representing a New Body Shape for the Family

Osteological observations were made on specimens cleared and counterstained (CS) for cartilage and bone according to a modified version of the method of Dingerkus and Uhler

How Do Bisphosphonates Inhibit Bone Metastasis In Vivo

On day 35 after tumor cell inoculation, radiographs of anesthetized mice were taken with the use of MIN-R2000 film in an MX-20 cabinet x-ray system

The Contribution of Habitat Loss to Changes in Body Size, Allometry, and Bilateral Asymmetry in Two Eleutherodactylus Frogs from Puerto Rico

We obtained radiographs of the specimens with a Faxitron Specimen Radiography System at the U.S. Geological Survey National Wildlife Health Center

A Runx2 threshold for the cleidocranial dysplasia phenotype

For radiographic analysis, the adult animals were scarified, de-skinned and organs were removed. The calvaria were isolated. All of the specimens were fixed in 100% ethanol. After 4 days, the specimens were placed on X-ray film and X-rays were taken

Novel Compound Enables High-Level Adenovirus Transduction in the Absence of an Adenovirus-Specific Receptor

Bone formation was analyzed by X-ray analysis, using an MX-20 specimen radiography system model

Antitumor Effects of Clinical Dosing Regimens of Bisphosphonates in Experimental Breast Cancer Bone Metastasis

For both protocols, on day 32 after tumor cell inoculation, radiographs of anesthetized mice were taken with the use of MIN-R2000 film in an MX-20 cabinet X-ray system

Enamel Defects and Ameloblast-specific Expression inEnam Knock-out/lacZKnock-in Mice*

Hemi-mandibles of 2-week-old mice were freed from soft tissues and radiographed using a Faxitron x-ray cabinet

Targeting Lyn inhibits tumor growth and metastasis in Ewing's sarcoma

To assess bone tumor formation and lung metastasis, Lynsi clone 10 cells were injected into the right tibia under anesthesia. Four weeks later, digitized radiographic images were taken using a MX-20 Specimen Radiograph System

Osterix, a Transcription Factor for Osteoblast Differentiation, Mediates Antitumor Activity in Murine Osteosarcoma

Transfection of the osx gene into the mouse osteosarcoma cells inhibited tumor cell growth in vitro and in vivo and significantly reduced tumor incidence

Vascular growth and remodeling in compensatory lung growth following right lobectomy

The main pulmonary artery was ligated under pressure with suture, and the lungs were inflation fixed by tracheal installation of 4% paraformaldehyde under constant pressure

The Activity of Zoledronic Acid on Neuroblastoma Bone Metastasis Involves Inhibition of Osteoclasts and Tumor Cell Survival and Proliferation

mice purchased from Harlan Sprague-Dawley were anesthetized with 2.5% isoflurane in 97.5% O2 and tumor cells were injected locally into the bone marrow cavity of the right femur

Relationship between eggplant seed morphology and germination1

The X-ray test was done with eight replications of 25 seeds, placed on double-faced adhesive tape on a transparent plastic sheet; the seeds were numbered according to their position on the sheet , so they could be identified later

Notch Inhibits Osteoblast Differentiation and Causes Osteopenia

Radiography was performed on killed 2-wk-old NICD transgenic mice on a Faxitron x-ray system

Molecular Genetic and Gene Therapy Studies of the Musculoskeletal System

Bone density and bone geometry measurements have been made by pQCT and Faxitron X-Ray analysis to establish basal values and to follow fracture healing

Osteoprotegerin Diminishes Advanced Bone Cancer Pain

The extent of sarcoma-induced bone destruction (osteolysis) was assessed radiologically at a 4x magnification using Faxitron analysis

Overcoming Dormancy and Enhancing Germination of Sphaeralcea munroana Seeds

Mechanically scarified seeds exhibited greater (P < 0.0001) mass gain compared with the boiling water scarification at the end of the 24-h observation period

A novel function for p21Cip1 and acetyltransferase p/CAF as critical transcriptional regulators of TGFbmediated breast cancer cell migration and invasion

Digital radiography of the hind limbs of all animals was used to monitor the development of skeletal lesions at four, six and eight weeks post-injection in a MX-20 cabinet X-ray system

BU-32: a novel proteasome inhibitor for breast cancer

On day 35 after tumor cell inoculation, radiographs of anesthetized mice were taken.

Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice

X-rays of mice were taken by the Faxitron MX-20 Specimen Radiography System using a Kodak Portal Oncology film

Optical Properties and Application of Metallic Nanoparticles and their Assembled Superstructures

To obtain histological photographs, rat tails were saved in 10% buffered formalin for 3 days. Tails were then decalcified with formic acid for 4-7 days and monitored with a Faxitron MX-20 X-ray system.

Neural Crest Deletion of Dlx3 Leads to Major Dentin Defects through Downregulation of Dspp

High-resolution X-rays were performed using a Faxitron MX-20 and Kodak XTL2 films. Micro-CT analysis was performed using a desktop X-ray microfocus CT scanner

The effect of versican G3 domain on local breast cancer invasiveness and bony metastasis

For analysis, fine detail radiographs were taken of murine appendicular bones

Cyr61 Expression in Osteosarcoma Indicates Poor Prognosis and Promotes Intratibial Growth and Lung Metastasis in Mice

Primary osteosarcoma biopsies of 60 patients and normal bone tissue specimens were collected between June 1990 and December 2005 according to the regulations of the local ethical committee

Host-derived RANKL is responsible for osteolysis in a C4-2 human prostate cancer xenograft model of experimental bone metastases

All animals were sacrificed 8 weeks after tumor-cell injection. Prior to sacrifice, all mice were radiographed with a Model MX-20 Laboratory radiography System

Distinct roles for intrinsic osteocyte abnormalities and systemic factors in regulation of FGF23 and bone mineralization in Hyp mice

The radiography of femurs was performed with the Faxitron specimen radiography system MX-20

A new species of casque-headed tree frog, genus Aparasphenodon Miranda-Ribeiro (Amphibia: Anura: Hylidae), from the Atlantic Rainforest of southern Bahia, Brazil

X-ray images of the holotype were used to corroborate generic assignment made through external morphology evidences

A Novel in vivo Role For OPGL in Activation Of Monocyte Effector Function and Inflammatory Response

The paws were severed with an axial cut of the distal radius/ulna (front paw) and tibia/fibula (hind paw). The samples were then imaged with a digital planar x-ray system

Hypomaturation Enamel Defects inKlk4Knockout/LacZ Knockin Mice

Hemimandibles from 7-week-old mice were cleaned of soft tissues and radiographed using a Faxitron x-ray cabinet model MX-20

Sarcoma Derived from Cultured Mesenchymal Stem Cells

Whole-body radiographs were taken under x5 magnification using a Faxitron Specimen Radiography System

Differential Effect of Doxorubicin and Zoledronic Acid on Intraosseous versus Extraosseous Breast Tumor Growth In vivo

PBS were inoculated into the tail vein of anesthetized nude mice. Radiographs were taken with a cabinet X-ray system and bone tumors were enumerated.

Prolonged Antiresorptive Treatment of Lytic Prostate Cancer Xenografts in Mouse Bone Results in Tumor Necrosis

Radiographic images were obtained using a digital MX-20 specimen radiography system

Conditional Deletion of Gremlin Causes a Transient Increase in Bone Formation and Bone Mass*

Radiography was performed on anesthetized or sacrificed mice on a Faxitron x-ray system

Pathogenic Role of FGF23 in Hyp Mice

The femurs from 6 week-old mice were collected and fixed in 70% ethanol. The radiography of femur was performed using a Faxitron MX-20 Specimen Radiography System

BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/-catenin signaling

The microfocal X-ray source is comprised of a tungsten anode with beryllium exit window, has a focal spot of 20 m, and was operated at 28 KeV

HES1 (Hairy and Enhancer of Split 1) Is a Determinant of Bone Mass

X-Rays were performed on eviscerated mice at an intensity of 30 kW for 20 s on a Faxitron X-Ray system

Runx2 overexpression in bone marrow stromal cells accelerates bone formation in critically-sized femoral defects

Every 4 weeks following surgery, 2-dimensional X-ray images of each sample were non-invasively obtained using an MX-20 Specimen Radiography System

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment leading to loss of stem cells and excessive myelopoiesis

Hind limbs were excised, fixed in 10% formalin and stored in 70% ethanol prior to x-ray and micro-CT analysis. X-rays were performed using a Faxitron MX-20 radiographic system

Osteoactivin Promotes Breast Cancer Metastasis to Bone

Immediately before sacrifice, mice were anesthetized and digital X-rays were obtained with a Faxitron Specimen Radiography System

Hind Limb Malformations in Free-Living Northern Leopard Frogs (Rana pipiens) From Maine, Minnesota, and Vermont Suggest Multiple Etiologies

All radiographs were taken to provide a ventraldorsal view, using a Faxitron Specimen Radiography System model MX-20

Phenotypes in mTERT+/- and mTERT-/- mice are due to short telomeres, not telomere-independent functions of TERT

To analyze mouse ribs, mice were sacrificed by CO2 asphyxiation prior to X-ray analysis and imaged using a Faxitron model MX-20 X-ray machine

HE3235 Inhibits Growth of Castration-Resistant Prostate Cancer1

Effects of tumor growth and HE3235 treatment on bone was examined using radiographs

The WWOX Tumor Suppressor Is Essential for Postnatal Survival and Normal Bone Metabolism

Radiography of dissected limbs at ages 7, 12, 17, and 20 days was performed after fixation in 4% paraformaldehyde at 4 °C under vacuum 2 days and rinsing in PBS using a Faxitron MX-20

Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer

Radiographs were then taken 21 or 30 days after tumor cell inoculation using a cabinet X-ray system

Blockade of Epidermal Growth Factor Receptor Signaling Leads to Inhibition of Renal Cell Carcinoma Growth in the Bone of Nude Mice

The mice were anesthetized weekly beginning 3 weeks after tumor cell injection, at which time they underwent digitized radiographic imaging with a Faxitron MX-20 X-ray unit

Taxonomic revision of thorny catfish genus Hassar

Measurements were made preferentially on the left side of the body using digital calipers and a stereomicroscope

Previously undescribed dental arrangement among electric knifefishes, with comments on the axonomic and conservation status of Tembeassu marauna Triques

Holotype and paratypes of Tembeassu marauna, as well as some specimens representative of additional apteronotid species from the upper Paraná and São Francisco river systems were x-rayed with aid of a Faxitron Digital X-Ray System

Activation of the RalGEF/Ral Pathway Promotes Prostate Cancer Metastasis to Bone

To monitor the development of bone metastasis, mice were radiographed weekly using an MX-20 Faxitron X-ray system

Direct and Bystander Killing of Sarcomas by Novel Cytosine Deaminase Fusion Gene

Radiographs of femora were performed and bone destruction scores were assessed

DNA methylation of SPARC and chronic low back pain

Aging WT mice were anaesthetized and x-rays were obtained using a Faxitron 3000

Photodynamic therapy of diseased bone

We have recently acquired a digital Faxitron unit that will allow us to follow the progression of osteolytic degradation within the bone

Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastasis in breast cancer.

Radiographs were taken 21 or 30 days after tumor cell injections using a cabinet X-ray system

Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease

High-resolution radiographs were taken at 26 kV with a 10 s exposure using a Faxitron MX-20 radiography system

NF-kB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF

Three weeks after injection, radiographs were taken using a Faxitron MX-20 X-ray machine

Ontogeny of corticotropin-releasing factor effects on locomotion and foraging in the Western spadefoot toad (Spea hammondii)

At the end of the hour, animals were anesthetized with 0.005% benzocaine and X-ray images were taken with a Specimen Radiograph System

Improving Bone Formation in a Rat Femur Segmental Defect by Controlling Bone Morphogenetic Protein-2 Release

A high-resolution radiograph of each femur with the stabilized defect was obtained using a Faxitron X-ray system

Novel and Selective Small Molecule Stimulators of Osteoprotegerin Expression Inhibit Bone Resorption

After 3 and 4 weeks of treatment, tumor progression was evaluated using a high resolution Faxitron X-ray system

Characterization of an MPS I-H knock-in mouse that carries a nonsense mutation analogous to the human IDUA-W402X mutation

Mice were anesthetized with isoflurane and examined using a Specimen Radiography System MX-20

Earlier Debridement and Antibiotic Administration Decrease Infection

A high-resolution radiograph of each femur with stabilized defect was obtained using a Faxitron X-ray system

Misexpression of CCAAT/enhancer binding protein beta causes osteopenia

The mice were anesthetized with tribromoethanol and the X-rays were performed at an intensity of 30 kw for 20 s on a Faxitron X-ray system

Regulation of osteoblastogenesis and bone mass by Wnt10b

For microradiographic analysis, anesthetized mice were analyzed with Faxitron Specimen Radiography System Model MX-20

Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia

Neutropenia and related infections are the most important dose-limiting toxicities in anticancer chemotherapy and radiotherapy

Biocompatibility and Bone Formation of Flexible, Cotton Wool-like PLGA/Calcium Phosphate Nanocomposites in Sheep

For detailed radiographs, bone specimens were cut perpendicular to the bone defect using a band saw, and bone blocks were documented with a Faxitron

Proteolytic Processing of Dentin Sialophosphoprotein (DSPP) Is Essential to Dentinogenesis

The mandibles from the 3-month-old and 6-month-old mice were dissected from the four groups of mice and analyzed with the Faxitron MX-20 Specimen Radiography System

Neurochemical and Cellular Reorganization of the Spinal Cord in a Murine Model of Bone Cancer Pain

The extent of bone destruction in tumor-injected femora was radiologically assessed using either standard x-ray film or Faxitron analysis

A Proteasome Inhibitor, Bortezomib, Inhibits Breast Cancer Growth and Reduces Osteolysis by Downregulating Metastatic Genes

Osteolysis was monitored by serial radiographs using a Faxitron MX-20 X-ray machine unit

A mouse model for cystinuria type I

X-rays were taken using the Faxitron Specimen Radiography System


High-detail radiographs were made, using a cabinet radiographic machine with non-screen films

Perfluorodecalin And Bone Regeneration

Levels of radiopacity were given in units of Bone Mineral Density and radiographs were taken with an X-ray camera

Evaluating desiccation sensitivity of Quercus rubra acorns using X-ray image analysis

Each acorn was labeled and placed cup scar down in a 3 cell × 4 cell indented carton and X-rayed

Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity

Radiographic images were obtained using a Faxitron MX-20 Digital Radiography system

Phenotypic plasticity in female naked mole-rats after removal from reproductive Suppression

A Faxitron MX-20 specimen x-ray cabinet was used to obtain radiographs of each mole-rat

Prevention of Cartilage Degeneration and Gait Asymmetry by Lubricin Tribosupplementation in the Rat Following Anterior Cruciate Ligament Transection

All animals were killed on day 70 after surgery, and anteroposterior and lateral radiographs of each knee were obtained using a high-resolution radiography system

A mouse model of early-onset renal failure due to a xanthine dehydrogenase nonsense mutation

Skeletons of mice fixed in 10% formalin after terminal anaesthesia were subjected to digital radiography at 26kV for 3 seconds using a Faxitron MX-20 digital X-ray system

Relationship between germination and bell pepper seed structure assessed by the X-ray test

This study was performed primarily to establish experimental procedures and verify the effectiveness of the X-ray test to detect damage or abnormalities in bell pepper

Impaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice

Radiographies of anaesthetized adults were obtained by using a Faxitron x-ray system

A Novel Role of Periostin in Postnatal Tooth Formation and Mineralization

To measure changes in the incisors, radio-graphs were taken using a Faxitron model MX-20 Specimen Radiography System with a digital camera attached

Assessing Growth and Response to Therapy in Murine Tumor Models

Radiographs are generated using a Faxitron MX-20 small-animal X-ray device

Seed weight of Xylopia aromatica (Annonaceae): quality evaluation from X-ray and seedling emergence

Following this, the seeds were distributed into the cells of an acrylic plate and X-rayed with a Faxitron X Ray MX - 20

Experimental manipulation of radiographic density in mouse mammary gland

5 days after experimental manipulations x-ray images of anaesthetized mice were taken using Faxitron Specimen Radiography System

X-ray Radiation Effects on Germination and Growth of Echinacea angustifolia

On April 2, 2012 I irradiated each envelope individually according to its pre-determined dosage using a Faxitron MX-20 model x-ray machine

Multimodal Imaging Analysis of Tumor Progression and Bone Resorption in a Murine Cancer Model

Anesthetized mice were radiographed using a Faxitron X-ray Instrument

Assessing viability of northern red oak acorns with X-rays

For our work with northern red oak acorns we used a Faxitron X-ray machine

Human Cell Surface Receptors as Molecular Imaging Candidates for Metastatic Prostate Cancer

Radiographs were taken 3, 4, 5 and 6 weeks after tumor cell injection using a Faxitron MX-20 machine

Inkjet-Based Biopatterning of Bone Morphogenetic Protein-2 to Spatially Control Calvarial Bone Formation

Traditional 2D radiographic images were collected from all fixed skulls using a Faxitron

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism

Plain radiographs  were taken on a HP Faxitron 43855A (skulls) or a Faxitron Mx-20 (long  bones)

Using X-Ray Image Analysis to Assess the Viability of Northern Red Oak Acorns: Implications for Seed Handlers

For northern red oak acorns in a Faxitron X-ray machine (MX-20, Faxitron X-ray Corporation, Wheeling, IL, USA), 190 seconds and 28 kilovolt potential (kVp) were found to yield the best images

Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice

The calvaria were radiographed using a Faxitron MX-20 Specimen Radiography System (Faxitron X-ray Corp., Wheeling, IL, USA) at an energy of 90 kV for 20 s

In situ application of non-thermal plasma: preliminary investigations for colorectal and lung tolerance

The position of the catheter was monitored using high resolution radiological imaging (MX-20, Faxitron X-ray Corporation, USA)

Cessation of Reproduction-Related Spine Elongation After Multiple Breeding Cycles in Female Naked Mole-Rats

Bone measurements were derived from radiographs of the subjects. A Faxitron MX-20 specimen x-ray cabinet (Wheeling, IL) was used to obtain radiographs of each mole-rat.

Accelerated Calvarial Healing in Mice Lacking Toll-Like Receptor 4

Ten animals from each group were euthanized 28 days after surgery and calvariae were harvested and fixed in 10% neutral buffered formalin for 24–48 hours. Radiographs were obtained using a Faxitron MX-20

Thrombin related peptide TP508 promoted fracture repair in a mouse high energy fracture model -Journal of Orthopaedic Surgery and Research

All the animals were anaesthetised and placed inside a high resolution digital radiography system (Faxitron MX-20, Faxitron X-ray Corporation). The faxitron was calibrated before the procedure at a standard X-ray dose of 24KV for 3 seconds at a distance


Various species of insects, among them flies (diptera), moths (lepidoptera), dragonflies (odonata) and beetles (coleoptera) have as-yet unmatched flight performance and increasingly understood muscular and nervous systems

Regulation of Breast Cancer-induced Bone Lesions by -Catenin Protein Signaling

Mice tibiae were harvested and fixed in 4% paraformaldehyde. Each bone sample was radiographed with a MX-20 x-ray system

Susceptibility of Various Life Stages of Rhyzopertha dominica (Coleoptera: Bostrichidae) to Flameless Catalytic Infrared Radiation

Kernels from each vial were spread into a single layer on a sample holder and subjected to X-rays from a Faxitron X-ray device

Are We Misinterpreting Seed Predation in Palms?

Predation of nonperforated seeds was evaluated using a Faxitron X-ray machine – model MX-20

Optimization of Cucumber Doubled Haploid Line Production Using In Victro Rescue of In Vivo Induced Parthenogenic Embryos.

Seeds were dried for 1 h, at 25˚C, in a flow hood chamber, and inserted in a sterile Omnitray (Nalge Europe Ltd., Hereford, U.K.) with lid. This dish was placed on a black and white Polapan 52 film and introduced in a Faxitron model MX-20 cabinet

Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats

Radiographic images of ipsilateral tibia were taken following fixation on Day 20, using a digital camera inside an enclosed cabinet during exposure to an X-ray source (Faxitron MX-20) for 10 s at 25 kVp

Impaired intranuclear trafficking of Runx2 (AML3CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo

The formation of osteolytic lesions in bones was assessed by radiography using a Faxitron MX-20

Dendritic cells loaded with FK506 kill T cells in an antigen-specific manner and prevent autoimmunity in vivo

Radiographs (Faxitron MX-20 cabinet x-ray system) and hematoxylin and eosin stained sections were scored by a board-certified blinded veterinary pathologist

Characterizing the BMP pathway in a wild type mouse model of distraction osteogenesis

Antero-posterior and lateral X-ray views of the operated tibiae were taken using a Faxitron X-ray machine

Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis

Mice were x-rayed in a prone and lateral position using a Digital Faxitron MX-20 with digital camera (Faxitron x-ray, Wheeling, IL), as described previously

Lytic Bone Lesions in Human Neuroblastoma Xenograft Involve Osteoclast Recruitment and Are Inhibited by Bisphosphonate1

High-resolution radiographs were taken under inhalation anesthesia (1.5% isoflurane in 98.5% O2; Abbott Lab., North Chicago, IL) at weekly intervals with a Faxitron X-ray machine

Using X-Rays to evaluate fissures in rice seeds dried artificially1

The radiation intensity and exposure time, which permitted the best visualization of the internal fissures of the rice seeds, was 14 kV for 360 seconds, as described by Menezes et al. (2005), using Faxitron MX-20 X-Ray equipment.

Mechanical regulation of vascular growth and tissue regeneration in vivo

One representative sample per group was chosen for histology based on qualitative Faxitron evaluation of bone growth


The images included in Figure 6, obtained from digital equipment (Faxitron MX-20), permit the detection of differences regarding the area filled by the embryo and show that the X-rays produced by this equipment allowed a more precise evaluation


A Faxitron MX-20 x-ray machine was used to classify the seeds

2-Butoxyethanol Female-Rat Model of Hemolysis and Disseminated Thrombosis: X-Ray Characterization of Osteonecrosis and Growth-Plate Suppression

The objective of the present investigation was to apply a noninvasive, high-magnification X-ray analysis, the Faxitron radiography system, to characterize the protracted bone damage associated with this 2-butoxyethanol model and to validate it by histopath

Dual-Energy Technique at Low Tube Voltages for Small Animal Imaging

The system consists of a microfocal X-ray source, and a CsI-coupled CMOS detector. The microfocal X-ray source (MX-20, Faxitron, USA), comprised of a tungsten anode with beryllium exit window, can be operated between 20 to 35 kV, and can yield a focal spo

The inadequacy of standard radiographs in detecting flaws in the cement mantle

Radiological assessment of the cement mantle is used routinely to determine the outcome of total hip replacement. We performed a simulated replacement arthroplasty on cadaver femora and took standard postoperative radiographs. The femora were then section

Pelvic-Fin Brooding In a New Species of Riverine Ricefish

A new species of ricefish is described from a hill stream in Tana Toraja, Sulawesi. Radiographs were taken with Faxitron's Digital Radiography System, the LX-60 .

Optimal bone strength and mineralization requires the type 2 iodothyronine deiodinase in osteoblasts

Faxitron Imaging. Digital x-ray images of long bones and tail vertebrae at 10- μm resolution were recorded using a Qados Faxitron MX20 variable kV point projection x-ray source (Cross Technologies plc.) (SI Materials and Methods).

Non-destructive x-ray testing of medical devices and tissue explants

"We invested in the Faxitron MX-20 Radiography System, used in medical, forensic, scientific and agricultural applications. It provides on-the-spot images in seconds and can export in most formats. Never have we been so well equipped"

Improved high-throughput bioassay for Rhyzopertha dominica (F.) (Coleoptera: Bostrichidae)

Bioassay diets were X-rayed as previously described (Guedes et al., 2010). Images of insects were obtained using a Faxitron MX-20 specimen radiography system with a 14-bit digital camera (Faxitron Bioptics, LLC., Tucson, AZ, USA).

Seed Production Used to Determine Pollen Limitation in Helianthus Sp.

In this study, we used Helianthus strumosus and Helianthus microcephalus to determine if seed set accurately corresponds with pollen treatments: open pollinated and cross-pollinated flowers would show a higher seed set than self-pollinated and non-pollina

Dual-Energy Technique at Low Tube Voltages for Small Animal Imaging

The system consists of a microfocal X-ray source, and a CsI-coupled CMOS detector. The microfocal X-ray source (MX-20, Faxitron, USA), comprised of a tungsten anode with beryllium exit window, can be operated between 20 to 35 kV, and can yield a focal spo

Commissioning and evaluation of a new commercial small rodent x-ray irradiator

An appropriate radiation source is essential in studies of tissue response in animal models. This paper reports on the evaluation and commissioning of a new irradiator suitable for studies using small animals or cell culture. The Faxitron is a 160-kVp ...

Faxitron Cephalometric Analysis of Tooth Movement Following Selective Alveolar Decortication

Objective: Using faxitron imaging, to cephalometrically analyze the magnitude of tooth movement as a function of time post alveolar decortication in the rat model.

Development of Craniofacial Structures in Transgenic Mice with Constitutively Active PTH/PTHrP Receptor

Craniofacial structures were radiographed using a Faxitron MX-20 Specimen Radiography System at energy of 30 kV for 90 s. The images were captured with Eastman Kodak X-OMAT TL film.

High resolution radiography is a relatively inexpensive imaging technique that can provide much information and detail about small animal skeletal and soft tissue features from specimens, or from intact and live animals.

The Faxitron® system has been and continues to be widely used for high resolution radiographic evaluation for biopsy specimens, forensics, archaeology, anthropology and other purposes.

Animal Modeling of Interventions to Promote Fracture Healing in the Face of Adverse Comorbidities

Work performed at the Midwest Orthopaedic Research Foundation, Minneapolis, MN

A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia

Oculodentodigital dysplasia (ODDD) is an autosomal dominant disorder characterized by pleiotropic developmental anomalies of the limbs, teeth, face and eyes that was shown recently to be caused by mutations in the gap junction protein alpha 1 gene (GJA1),