Clinical Findings | Faxitron Bioptics LLC
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Comparison of intra-operative specimen mammography to standard specimen mammography for excision of non-palpaple breast lesions: a randomized trial.

Standard specimen mammography (SSM) is performed in the radiology department after wire-localized excision of non-palpable breast lesions to confirm the presence of the target and evaluate margins. Alternatively, intra-operative specimen mammography (ISM)

Intraoperative Radiological Margin Assessment in Breast-Conserving Surgery

In breast-conserving surgery (BCS), the main objective is to obtain negative histological margins which are known to be a major prognostic factor for tumor recurrence.

Network meta-analysis of margin threshold for woman with ductal carcinoma in situ

Within cosmetic constraint, surgeons should attempt to achieve negative margins as wide as possible in their first attempt

Optimizing Surgical Margins in Breast Conservation

Intraoperative specimen radiography using the Faxitron can be done immediately after specimen excision. The Faxitron allows the surgeon to visualize an eccentric location of a tumor or clip so that additional tissue can be removed...

Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer

The cumulative incidence of recurrent tumor in the ipsilateral breast was 14.3 percent in the women who underwent lumpectomy and breast irradiation, as compared with 39.2 percent in the women who underwent lumpectomy without irradiation

Intraoperative digital specimen mammography: a significant improvement in operative efficiency

The goal of this study was to determine the length of operative time and its effect on surgeon productivity with the use of intraoperative digital specimen mammography compared to standard specimen mammography.

Incidence and Consequence of Close Margins for Ductal Carcinoma In Situ Treated with Mastectomy

The impact of close or positive margins for DCIS treated with mastectomy is unclear and may lead to post-mastectomy radiotherapy (PMRT). This study is the largest reported cohort of women with DCIS treated with mastectomy examining the incidence and clini

Factors correlating with reexcision after breast-conserving therapy

At least one repeat operation was necessary in 121 patients (21.4%), and mastectomy was ultimately necessary in 54 patients (9.6%)

Breast Microcalcifications: Retrieval Failure at Prone Stereotactic Core and Vacuum Breast Biopsy Frequency, Causes, and Outcome

Failure to retrieve microcalcifications was least common with 11-gauge directional vacuum-assisted biopsy and occurred in 1% (19 of 1423) of lesions

An evaluation of intraoperative digital specimen mammography versus conventional specimen radiography for the excision of nonpalpable breast lesions

This study examined the impact of intraoperative digital specimen mammography (IDSM) compared with conventional specimen radiography (CSR) for nonpalpable breast lesions in patients undergoing breast-conserving surgery (BCS).

Accuracy of intra-operative touch prep frozen-section analysis of breast cancer lumpectomy bed margins

Intraoperative analysis of margins using FSA is effective at minimizing the number of additional operations, with 19 patients benefiting from immediate intervention in this study

In-Theatre Intra-Operative Specimen Radiography Reduces Re-Operation Rates For Margin Positivity After Breast Conserving Surgery

There is a significant reduction in reoperation rates since the introduction of the in-theatre IOSR by 16% (p=0.007). The mean specimen weight has remained unchanged. Although the numbers are small, reoperation rates are particularly high in patients...

Trends in image quality in high magnification digital specimen cabinet radiography

The results above demonstrate that significant improvements in the overall image quality of specimen cabinet radiography can be achieved when using the high magnification geometry available with the digital Faxitron MX20 unit

Lean Redesign of Digital X-Ray of Breast Biopsies for Calcifications Reduction of Turn around Time and Wasteful Recuts in the Henry Ford Production System

Lean process redesign utilizing DXR up-front in the gross examination process of breast biopsies, has significantly improved TAT by 60% and number of recuts has reduced by 75% for breast biopsies for calcifications. This improvement in TAT and decrease...

Should Surgeons Interpret Breast Intraoperative Digital Specimen Radiographs? We Can All Identify a Clip, But Margins Are a Different Question

After institutional review board (IRB) approval, we prospectively compared breast cancer IDSR interpretations by both a board certified radiologist and surgeon. We compared 30 consecutive breast cancer excisions using a Faxitron Bioptics piXarray, IDSR in

Trends in image quality in high magnification digital specimen cabinet radiography

A recently introduced model, the MX20 (Faxitron, Wheeling, USA) features a nominal focal spot size of only 0.02 mm, a receptor–focus distance of 58 cm, magnification geometry of up to 6 5 and a digital receptor consisting of a 5 cm 6 5 cm charge coupled d

The Association of Measured Breast Tissue Characteristics with Mammographic Density and Other Risk Factors for Breast Cancer

We have examined the relationships between the measured properties of breast tissue and mammographic density and other risk factors for breast cancer, using breast tissue obtained at forensic autopsy and not selected for the presence of abnormalities.

Two-View Specimen Radiography in Surgical Biopsy of Nonpalpable Breast Masses

Nonpalpable, low-density, noncalcified lesions sometimes can be difficult to see on an initial specimen radiograph. In 57 consecutive wire localizations, 37 patients had obvious microcalcifications and did not require a second specimen radiograph. Twentys

Processing Stereotactic Breast Biopsy Specimens: Impact of Specimen Radiography System on Workflow

The Faxitron unit allows for quickly evaluating the core tissue specimens in the biopsy room and efficiently transferring them to the collection jars sent to pathology. Otherwise, the core tissue specimens must be taken out of the biopsy room to the ...

Intra-operative specimen analysis using Faxitron microradiography for excision of mammographically suspicious, non-palpable breast lesions

Recent advances in digital imaging have made Faxitron microradiography an attractive alternative to intra-operative conventional specimen radiography (CSR) for the excision of wire-localized breast lesions.

Intra-operative Digital Specimen Radiography of Sentinel Lymph Nodes as an Alternative to Frozen Section Diagnosis

Frozen section analysis is the established modality to diagnose breast cancer metastasis to sentinel lymph node/nodes (SLN). Studies using ultrasound imaging of axillary lymph nodes to predict metastasis opens the possibility of alternative...

High resolution intra-operative two-dimensional specimen mammography and its impact on second operation for re-excision of positive margins at final pathology after breast conservation surgery

A retrospective review of 128 patients who underwent breast conservation surgery for early breast cancer was performed using intraoperative 2-dimensional Faxitron high-resolution specimen mammography...

Wedge Case Study

The Faxitron® Wedge™ allowed a true and precise orthogonal view that guided the surgeon to take additional tissue. This avoided a re-excision surgery that would have been required had just a single planar specimen radiograph been acquired.

Intraoperative Assessment of the Breast

Excisional biopsies are usually performed to completely remove a palpable or mammographically detected lesion. For mammographic lesions, a specimen radiograph (Faxitron) is obtained (see ‘‘Gross Examination’’) and compared with the preoperative mammogram

A Unique Use of Intraoperative Digital Specimen Radiography (IDSR) in the Treatment of Primary Hyperparathyroidism

Resected parathyroid specimens were evaluated with the Faxitron Bioptics PiXarray100 digital radiograph system and pathologic evaluation. Thirty-six patients with primary hyperparathyroidism met eligibility criteria. Thirty-nine (n=39) specimens were eval

Analysis of the use of specimen mammography in breast conservation therapy

Specimen mammography can help reduce reoperation rate by identifying patients who need additional margin excision at the time of initial surgery for breast conservation therapy. Using two-view specimen mammography, our reoperation rate was reduced from 12

Faxitron BioVision Imaging versus Analog Xray for Patients Undergoing Excisional Biopsies by Wire Localization

Xray imaging is the standard of care for verifying adequate excision in patients undergoing breast biopsies by wire localization. A number of studies have evaluated the use of Faxitron BioVision (Faxitron Bioptics, Tucson, AZ).

Method to Study the Rapid Intraoperative Prediction of Sentinel Node Positivity

In order to compare the combined benefit of intraoperative physical examination of the sentinel nodes along with intraoperative imaging, we invited both the surgeons and the radiologists to participate in this project.

Comparison of Dedicated Digital Specimen Radiography with Direct Digital Specimen Mammography Images

Specimen radiography is a long established procedure for confirming the presence of both calcifiedand noncalcified targeted lesions after needle localization and surgical excision(1,2) and to confirm the presence of targeted microcalcification.

CMOS Technology for Intraoperative Digital Imaging: Can the Re-excision Rate after Breast Surgery be Reduced?

A retrospective clinical study was done to investigate whether a new intraoperative digital imaging system (BioVision™) could reduce the rate of re-excisions compared to a commercial FFDM system.