• NOT FOR CLINICAL USE.

Pre-Clinical Imaging

Small animal models are commonly used to study conditions from metastatic cancer to obesity and osteoporosis. Hologic’s Faxitron® cabinet x-ray systems allow scientists and researchers to screen, track, and evaluate disease and structural changes in longitudinal studies.

Hologic brings you cabinet x-ray systems to screen, track, and evaluate structural, bone density, and body composition changes in longitudinal studies. Our solutions offer multiple detector sizes to match system performance to specific in vivo and ex vivo imaging applications. Get to know the Hologic pre-clinical imaging products and achieve your vision in pioneering clinically translatable findings.

Pre-clinical imaging applications include:
• Phenotyping
• Bone regeneration
• Tumor growth
• Body Composition
• Bone Mineral Content (BMC)
• Bone Mineral Density (BMD)

Faxitron® Pro x-ray cabinet

The Faxitron Pro digital x-ray cabinet was designed to be placed directly on the benchtop in your lab or wherever you need easy access to imaging. Multiple cabinet and detector sizes, coupled with a wide energy range from 20-100kV makes the Faxitron Pro cabinet line ideal for imaging a broad range of both biological and light NDT samples. The less than 15 µm focal spot and up to 10X geometric magnification provides up to 10 µm resolution images.

Faxitron® Pro x-ray cabinet

Features

  • Easy to use with a laser centering guide and window to ensure proper sample positioning and no requirements for extensive training or additional x-ray shielding
  • One button operation with advanced Automatic Exposure Control (AEC) to remove the guesswork from selecting appropriate exposure time and kV settings
  • Single-click calibration with auto object detect that allows for simple, error-free calibration
  • Convenient design featuring an easy to clean, stainless steel inner chamber and an integrated port for introduction of gaseous anesthesia lines or cables
  • High-resolution imaging via a 10X magnification tray which provides as high as 10 µm resolution. Images are instantaneously displayed on included 24″ high-resolution 3.7MPx monitor
  • Remote diagnostic and support from product specialists who put you and your research first

Faxitron Pro+ x-ray cabinet

Faxitron Pro+ x-ray cabinet is a larger, more versatile, fully shielded digital x-ray cabinet. Featuring an extra-large field of view so you can image large samples without sacrificing resolution.

Hologic Faxitron Pro+ Cabinet

Features

  • Large cabinet and detector size lets you image samples currently too big for existing cabinet x-ray systems thanks to an expanded cabinet and larger 17″ x 17″ (43cm x 43cm) imaging area.
  • Best-in-class resolution with native detector resolution of 100 µm and effective resolution up to 10 µm. Multiple levels of geometric magnification (up to 10X) allow imaging at the highest resolution.
  • More versatile thanks to proprietary Automatic Exposure Control (AEC) which selects optimal x-ray exposure settings to ensure one of the highest image quality for a broad range of biological and light NDT samples. Manual exposure mode also available for multi-layer samples and those containing a variety of components.
  • Ergonomic design means this fully integrated, floor standing system with heavy duty casters fits easily into any lab and plugs into any standard A/C outlet.
  • Easy to use with no extensive training or specialized x-ray knowledge required to operate. Intuitive software designed to meet the imaging needs of research and industrial users.
  • Independently certified by a Nationally Recognized Testing Laboratory (Intertek) to the highest international standards.
    Remote diagnostics and support available from product specialists ready to help

Pre-Clinical Research Documents

MISC-07124_REVIEW (082020) - A-Mouse-Model-of-Early-Onset-Renal-Failure-Due-to-a-Xanthine-Dehydrogenase-Nonsense-Mutation791.5 KBMISC-07123_REVIEW (082020) - A-Proteasome-Inhibitor-Bortezomib-Inhibits-Breast-Cancer-Growth-and-Reduces-Osteolysis-by-Downregulating-Metastatic-Genes586.6 KBMISC-07122_REVIEW (082020) - A-Rat-Model-of-Early-Stage-Osteonecrosis-Induced-by-Glucocorticoids1.3 MBMISC-07121_REVIEW (082020) - A-Self-Inactivating-γ-Retroviral-Vector-Reduces-Manifestations-of-Mucopolysaccharidosis-I-in-Mice392.4 KBMISC-07120_REVIEW (082020) - Biocompatibility-and-Bone-Formation-of-Flexible-Cotton-Wool-Like-PLGA-Calcium-Phosphate-Nanocomposites-in-Sheep768.3 KBMISC-07119_REVIEW (082020) - Cyr61-Expression-in-Osteosarcoma-Indicates-Poor-Prognosis-and-Promotes-Intratibial-Growth-and-Lung-Metastasis-in-Mice571.9 KBMISC-07117_REVIEW (082020) - DNA-Methylation-of-SPARC-and-Chronic-Low-Back-Pain1.8 MBMISC-07116_REVIEW (082020) - Dual-Energy-Technique-at-Low-Tube-Voltages-for-Small-Animal-Imaging-0635.6 KBMISC-07115_REVIEW (082020) - Dual-Function-of-ERRαin-Breast-Cancer-and-Bone-Metastasis-Formation-Implication-of-VEGF-and-Osteoprotegerin1.1 MBMISC-07114_REVIEW (082020) - Earlier-Debridement-and-Antibiotic-Administration-Decrease-Infection81.2 KBMISC-07113_REVIEW (082020) - A-Mouse-Model-for-Osseous-Heteroplasia1.2 MBMISC-07112_REVIEW (082020) - Alternate-Protein-Kinase-A-Activity-Identifies-a-Unique-Population-of-Stromal-Cells-in-Adult-Bone1.3 MBMISC-07082_Extracellular-Engagement-of-α6-Integrin-Inhibited-Urokinase-Type-Plasminogen-Activator-Mediated-Cleavage-and-Delayed-Human-Prostate-Bone-Metastasis483.8 KBMISC-07080_Enhancing-Quality-of-Life-for-Breast-Cancer-Patients-with-Bone-Metastases1.5 MBMISC-07079_Enamel-Defects-and-Ameloblast-Specific-Expression-InEnam-Knock-Out-lacZKnock-in-Mice1.5 MBMISC-07078_Effect-of-Zoledronic-Acid-on-the-Doxycycline-Induced-Decrease-in-Tumour-Burden-in-a-Bone-Metastasis-Model-of-Human-Breast-Cancer234.1 KBMISC-07077_Distinct-Roles-for-Intrinsic-Osteocyte-Abnormalities-and-Systemic-Factors-in-Regulation-of-FGF23-and-Bone-Mineralization-in-Hyp-Mice932.1 KBMISC-07076_Direct-and-Bystander-Killing-of-Sarcomas-by-Novel-Cytosine-Deaminase-Fusion-Gene866.8 KBMISC-07075_Differential-Effect-of-Doxorubicin-and-Zoledronic-Acid-on-Intraosseous-Versus-Extraosseous-Breast-Tumor-Growth-In-Vivo708.2 KBMISC-07074_Detection-of-Simulated-Inflicted-Metaphyseal-Fractures-in-a-Fetal-Pig-Model-Image-Optimization-and-Dose-Reduction-with-Computed-Radiography_0337.1 KBMISC-07073_Degenerative-Joint-Disease-of-the-Hip-in-Cats-Imaging-Pathologic-and-in-Vitro-Studies1.7 MBMISC-07071_Conditional-Deletion-Of-Gremlin-Causes-a-Transient-Increase-in-Bone-Formation-and-Bone-Mass844.0 KBMISC-07070_Characterization-of-an-MPS-I-H-Knock-in-Mouse-that-Carries-a-Nonsense-Mutation-Analogous-to-the-Human-IDUA-W402X-Mutation1.0 MBMISC-07069_Cessation-of-Reproduction-Related-Spine-Elongation-After-Multiple-Breeding-Cycles-in-Female-Naked-Mole-Rats1.1 MBMISC-07068_BU-32-a-Novel-Proteasome-Inhibitor-for-Breast-Cancer1.5 MBMISC-07067_Blockade-of-Epidermal-Growth-Factor-Receptor-Signaling-Leads-to-Inhibition-of-Renal-Cell-Carcinoma-Growth-in-the-Bone-of-Nude-Mice866.3 KBMISC-07066_Assessing-Growth-and-Response-to-Therapy-in-Murine-Tumor-Models1.5 MBMISC-07064_Antitumor-Effects-of-Clinical-Dosing-Regimens-of-Bisphosphonates-in-Experimental-Breast-Cancer-Bone-Metastasis966.0 KBMISC-07063_A-Novel-in-Vivo-Role-For-OPGL-in-Activation-Of-Monocyte-Effector-Function-and-Inflammatory-Response1.0 MBMISC-07062_A-New-Species-of-the-Neotropical-Catfish-Genus-Trichomycterus-Siluriformes-Trichomycteridae-Representing-a-New-Body-Shape-for-the-Family928.1 KB

Pre-Clinical Research Documents

MISC-07061_A-New-Species-of-Casque-Headed-Tree-Frog-Genus-Aparasphenodon-Miranda-Ribeiro-Amphibia-Anura-Hylidae-from-the-Atlantic-Rainforest-of-Southern-Bahia-Brazil543.6 KBMISC-07060_A-Mouse-Model-for-Cystinuria-Type-I569.5 KBMISC-07059_A-Gja1-Missense-Mutation-in-a-Mouse-Model-of-Oculodentodigital1.1 MBMISC-07058_A-Genetic-Screen-for-Modifiers-of-the-Delta1-Dependent-Notch-Signaling-Function-in-the-Mouse394.9 KBMISC-07057_A-Digenean-Metacercaria-Apophallus-sp.-and-a-Myxozoan-Myxobolus-sp.-Associated-with-Vertebral-Deformities-in-Cyprinid-Fishes-from-the-Willamette-River-Oregon630.1 KBMISC-07055_A-Comprehensive-Analysis-of-the-Dual-Roles-of-BMPs-in-Regulating-Adipogenic-and-Osteogenic-Differentiation-of-Mesenchymal-Progenitor-Cells1.4 MBMISC-07054_2-Butoxyethanol-Female-Rat-Model-of-Hemolysis-and-Disseminated-Thrombosis-X-Ray-Characterization-of-Osteonecrosis-and-Growth-Plate-Suppression547.0 KBMISC-07030_JNJ-28312141-Nvl-Orally-Act-Clny-Stim-Fctr-Rcptr-Rcptr-Tyrsn-Knse-Rcptr-Tyrosine-Kinase-Inhibit-Po-Utility-Sld-Tumors801.4 KBMISC-07029_Platelet-Derived-Lysophosphatidic-Acid-Supports-the-Progression-of-Osteolytic-Bone-Metastases-in-Breast-Cancer1.4 MBMISC-07028_Photodynamic-Therapy-of-Diseased-Bone227.5 KBMISC-07027_Photoacoustic-Tomography-of-Joints-Aided-by-an-Etanercept-Conjugated-Gold-Nanoparticle-Contrast-Agent-an-Ex-Vivo-Preliminary-Rat-Study528.2 KBMISC-07026_Osterix-a-Transcription-Factor-for-Osteoblast-Differentiation-Mediates-Antitumor-Activity-in-Murine-Osteosarcoma1.2 MBMISC-07024_Osteoactivin-Promotes-Breast-Cancer-Metastasis-to-Bone1.1 MBMISC-07023_Optimization-of-Cucumber-Doubled-Haploid-Line-Production-Using-In-Victro-Rescue-of-In-Vivo-Induced-Parthenogenic-Embryos._03.0 MBMISC-07022_Ontogeny-of-Corticotropin-Releasing-Factor-Effects-on-Locomotion-and-Foraging-in-the-Western-Spadefoot-Toad-Spea-Hammondii406.8 KBMISC-07021_Novel-Compound-Enables-High-Level-Adenovirus-Transduction-in-the-Absence-of-an-Adenovirus-Specific-Receptor184.4 KBMISC-07020_Notch-Inhibits-Osteoblast-Differentiation-and-Causes-Osteopenia881.8 KBMISC-07018_NF-kB-in-Breast-Cancer-Cells-Promotes-Osteolytic-Bone-Metastasis-by-Inducing-Osteoclastogenesis-Via-GM-CSF_0859.1 KBMISC-07017_NFATc1-in-Mice-Represses-Osteoprotegerin-During-Osteoclastogenesis-and-Dissociates-SystemiC-Osteopenia-from-Inflammation-in-Cherubism1.6 MBMISC-07016_Neurochemical-and-Cellular-Reorganization-of-the-Spinal-Cord-in-a-Murine-Model-of-Bone-Cancer-Pain1.9 MBMISC-07015_Mutation-of-Mouse-Mayp-Pstpip2-Causes-a-Macrophage-Autoinflammatory-Disease794.2 KBMISC-07013_Integrin-Avβ3-Expression-Confers-on-Tumor-Cells-a-Greater-Propensity-to-Metastasize-to-Bone1.5 MBMISC-07012_In-Situ-Application-of-Non-Thermal-Plasma-Preliminary-Investigations-for-Colorectal-and-Lung-Tolerance192.5 KBMISC-07011_Influence-of-Ribeiroia-Ondatrae-Trematoda-Digenea-Infection-Limb-Development-&-Survival-of-Nthrn-Leopard-Frogs-Rana-Pipiens-Effects-of-Host-Stage-&-Parasite-Exposure-Lvl478.0 KBMISC-07010_Increased-Dickkopf-1-Expression-in-Breast-Cancer-Bone-Metastases154.2 KBMISC-07009_Impaired-Intranuclear-Trafficking-of-Runx2-AML3CBFA1-Transcription-Factors-in-Breast-Cancer-Cells-Inhibits-Osteolysis-in-Vivo525.2 KBMISC-07008_Identification-of-the-Haematopoietic-Stem-Cell_Niche-and-Control-of-the-Niche-Size486.3 KBMISC-07007_Human-Cell-Surface-Receptors-as-Molecular-Imaging-Candidates-for-Metastatic-Prostate-Cancer285.5 KBMISC-07006_Host-Derived-RANKL-is-Responsible-for-Osteolysis-in-a-C4-2-Human-Prostate-Cancer-Xenograft-Model-of-Experimental-Bone-Metastases719.2 KBMISC-07005_Hind-Limb-Malformations-in-Free-Living-Northern-Leopard-Frogs-Rana-Pipiens-From-Maine-Minnesota-and-Vermont-Suggest-Multiple-Etiologies513.9 KBMISC-07004_High-Throughput-Behavioral-Screening-Method-for-Detecting-Auditory-Response-Defects-in-Zebrafish373.8 KBMISC-07003_Growing-Out-of-a-Caste–Reproduction-and-the-Making-of-the-Queen-Mole-Rat854.6 KBMISC-07002_Homozygous-Ablation-of-Fibroblast-Growth-Factor-23-Results-in-Hyperphosphatemia-and-Impaired-Skeletogenesis-and-Reverses-Hypophosphatemia-in-Phex-Deficient-Mice1.1 MB

Hologic | Sciences & NDT

Hologic’s increased portfolio dedicated to sciences and non-destructive testing, allows for scientists and researchers more timely discoveries and effective ways to ensure the integrity of their work in areas of pre-clinical, agriculture, and forensic imaging and non-destructive testing.
Hologic, Faxitron and the Science of Sure are trademarks and/or registered trademarks of Hologic, Inc., and/or its subsidiaries in the United States and/or other countries. For specific information on what products are available for sale in a particular country, please contact your local Hologic representative.

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